STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GATA6Transcription factor GATA-6; Transcriptional activator. (387 aa)    
Predicted Functional Partners:
LMCD1
LIM and cysteine rich domains 1.
    
 0.951
NKX2-5
Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Binds to the core DNA motif of promoter. Belongs to the NK-2 homeobox family.
   
 
 0.929
SOX17
Uncharacterized protein.
   
 
 0.883
SOX7
Uncharacterized protein.
    
 
 0.840
FOXA2
Fork-head domain-containing protein.
   
 
 0.832
ZFPM2
Zinc finger protein, FOG family member 2.
    
 0.832
ZFPM1
Zinc finger protein, FOG family member 1.
   
 0.743
TBX5
T-box transcription factor TBX5; DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. May bind to the core DNA motif of promoters.
   
 
 0.740
TBX3
T-box transcription factor TBX3; Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
   
 
 0.724
EOMES
T-box_assoc domain-containing protein.
   
 
 0.723
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.