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PPP1CB protein (Gallus gallus) - STRING interaction network
"PPP1CB" - Serine/threonine-protein phosphatase PP1-beta catalytic subunit in Gallus gallus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
PPP1CBSerine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity; Belongs to the PPP phosphatase family. PP-1 subfamily (327 aa)    
Predicted Functional Partners:
MYPT1
Protein phosphatase 1 regulatory subunit 12A; Regulates myosin phosphatase activity (1084 aa)
     
  0.996
PPP1CC
Gallus gallus protein phosphatase 1, catalytic subunit, gamma isozyme (PPP1CC), mRNA (323 aa)
   
0.974
SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72; May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination (194 aa)
     
  0.967
WDR82
WD repeat-containing protein 82; Component of a chromatin regulatory complex involved in regulating chromatin structure in the nucleus (313 aa)
     
  0.964
RB1
Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 ’Lys-20’ trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting c [...] (882 aa)
     
  0.943
WDR33
WD repeat domain 33 (1245 aa)
     
  0.942
PPP1R2
Gallus gallus protein phosphatase 1, regulatory (inhibitor) subunit 2 (PPP1R2), mRNA (210 aa)
     
 
  0.941
PPP1R3B
Protein phosphatase 1, regulatory subunit 3B (301 aa)
     
  0.934
PPP1R3C
Protein phosphatase 1, regulatory subunit 3C (319 aa)
       
  0.934
GYS2
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan (704 aa)
     
  0.928
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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