NHLRC2 protein (Gallus gallus) - STRING interaction network

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Score

NHLRC2

NHL repeat-containing protein 2; Required for normal embryonic development. (727 aa)

Predicted Functional Partners:

VWA2

0.713

MED4

0.700

INO80E

0.686

CHTF18

0.668

PLEKHF2

0.644

TM2D3

0.626

TM2D2

0.626

LAMTOR2

0.625

ABLIM1

0.603

POLR1B

0.602

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABLIM1	NHLRC2	ENSGALP00000014715	ENSGALP00000014530	Uncharacterized protein.	NHL repeat-containing protein 2; Required for normal embryonic development.	0.603
ABLIM1	VWA2	ENSGALP00000014715	ENSGALP00000014593	Uncharacterized protein.	Von Willebrand factor A domain containing 2.	0.601
CHTF18	NHLRC2	ENSGALP00000044268	ENSGALP00000014530	AAA domain-containing protein.	NHL repeat-containing protein 2; Required for normal embryonic development.	0.668
CHTF18	POLR1B	ENSGALP00000044268	ENSGALP00000057133	AAA domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.667
INO80E	MED4	ENSGALP00000074285	ENSGALP00000049161	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.715
INO80E	NHLRC2	ENSGALP00000074285	ENSGALP00000014530	Uncharacterized protein.	NHL repeat-containing protein 2; Required for normal embryonic development.	0.686
INO80E	PLEKHF2	ENSGALP00000074285	ENSGALP00000048710	Uncharacterized protein.	Pleckstrin homology domain-containing family F member 2; May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.	0.700
LAMTOR2	NHLRC2	ENSGALP00000058190	ENSGALP00000014530	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	NHL repeat-containing protein 2; Required for normal embryonic development.	0.625
LAMTOR2	TM2D2	ENSGALP00000058190	ENSGALP00000047356	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	TM2 domain containing 2.	0.539
LAMTOR2	TM2D3	ENSGALP00000058190	ENSGALP00000006409	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	TM2 domain-containing protein.	0.528
MED4	INO80E	ENSGALP00000049161	ENSGALP00000074285	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.715
MED4	NHLRC2	ENSGALP00000049161	ENSGALP00000014530	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	NHL repeat-containing protein 2; Required for normal embryonic development.	0.700
MED4	PLEKHF2	ENSGALP00000049161	ENSGALP00000048710	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Pleckstrin homology domain-containing family F member 2; May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.	0.702
MED4	POLR1B	ENSGALP00000049161	ENSGALP00000057133	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.514
NHLRC2	ABLIM1	ENSGALP00000014530	ENSGALP00000014715	NHL repeat-containing protein 2; Required for normal embryonic development.	Uncharacterized protein.	0.603
NHLRC2	CHTF18	ENSGALP00000014530	ENSGALP00000044268	NHL repeat-containing protein 2; Required for normal embryonic development.	AAA domain-containing protein.	0.668
NHLRC2	INO80E	ENSGALP00000014530	ENSGALP00000074285	NHL repeat-containing protein 2; Required for normal embryonic development.	Uncharacterized protein.	0.686
NHLRC2	LAMTOR2	ENSGALP00000014530	ENSGALP00000058190	NHL repeat-containing protein 2; Required for normal embryonic development.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.625
NHLRC2	MED4	ENSGALP00000014530	ENSGALP00000049161	NHL repeat-containing protein 2; Required for normal embryonic development.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.700
NHLRC2	PLEKHF2	ENSGALP00000014530	ENSGALP00000048710	NHL repeat-containing protein 2; Required for normal embryonic development.	Pleckstrin homology domain-containing family F member 2; May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.	0.644