node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRLS1 | LUC7L3 | ENSGALP00000069526 | ENSGALP00000048736 | Cardiolipin synthase 1. | Uncharacterized protein. | 0.604 |
CRLS1 | PGAP3 | ENSGALP00000069526 | ENSGALP00000034810 | Cardiolipin synthase 1. | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. | 0.703 |
CRLS1 | PIGM | ENSGALP00000069526 | ENSGALP00000037081 | Cardiolipin synthase 1. | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity). | 0.537 |
LUC7L3 | CRLS1 | ENSGALP00000048736 | ENSGALP00000069526 | Uncharacterized protein. | Cardiolipin synthase 1. | 0.604 |
LUC7L3 | PGAP3 | ENSGALP00000048736 | ENSGALP00000034810 | Uncharacterized protein. | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. | 0.674 |
LUC7L3 | PIGM | ENSGALP00000048736 | ENSGALP00000037081 | Uncharacterized protein. | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity). | 0.516 |
MPPE1 | PGAP1 | ENSGALP00000045371 | ENSGALP00000050886 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | Post-GPI attachment to proteins 1. | 0.464 |
MPPE1 | PGAP2 | ENSGALP00000045371 | ENSGALP00000070534 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | Post-GPI attachment to proteins 2. | 0.621 |
MPPE1 | PGAP3 | ENSGALP00000045371 | ENSGALP00000034810 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. | 0.658 |
MPPE1 | PIGK | ENSGALP00000045371 | ENSGALP00000014651 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. | 0.554 |
MPPE1 | PIGL | ENSGALP00000045371 | ENSGALP00000007144 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | Phosphatidylinositol glycan anchor biosynthesis class L. | 0.491 |
MPPE1 | PIGM | ENSGALP00000045371 | ENSGALP00000037081 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity). | 0.403 |
MPPE1 | PIGT | ENSGALP00000045371 | ENSGALP00000061557 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | Phosphatidylinositol glycan anchor biosynthesis class T. | 0.511 |
PGAP1 | MPPE1 | ENSGALP00000050886 | ENSGALP00000045371 | Post-GPI attachment to proteins 1. | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | 0.464 |
PGAP1 | PGAP2 | ENSGALP00000050886 | ENSGALP00000070534 | Post-GPI attachment to proteins 1. | Post-GPI attachment to proteins 2. | 0.410 |
PGAP1 | PGAP3 | ENSGALP00000050886 | ENSGALP00000034810 | Post-GPI attachment to proteins 1. | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. | 0.651 |
PGAP1 | PIGK | ENSGALP00000050886 | ENSGALP00000014651 | Post-GPI attachment to proteins 1. | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. | 0.638 |
PGAP1 | PIGM | ENSGALP00000050886 | ENSGALP00000037081 | Post-GPI attachment to proteins 1. | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity). | 0.568 |
PGAP1 | PIGT | ENSGALP00000050886 | ENSGALP00000061557 | Post-GPI attachment to proteins 1. | Phosphatidylinositol glycan anchor biosynthesis class T. | 0.631 |
PGAP2 | MPPE1 | ENSGALP00000070534 | ENSGALP00000045371 | Post-GPI attachment to proteins 2. | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity). | 0.621 |