Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HBBAHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. The beta chain is a component of adult hemoglobin A and D. (147 aa)    
Predicted Functional Partners:
HBA1
Hemoglobin subunit alpha-A; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family.
  
0.996
HBAD
Hemoglobin subunit alpha-D; Involved in oxygen transport from the lung to the various peripheral tissues.
  
0.996
HBZ
Hemoglobin subunit pi; The pi' chain is the counterpart of the alpha chain in the major early embryonic hemoglobin P; Belongs to the globin family.
  
0.969
HBE1
Beta-H globin; Belongs to the globin family.
  
0.948
HBBR
Hemoglobin subunit rho; The rho chain is the major early embryonic beta-type hemoglobin chain.
  
 
0.920
PIT54
Uncharacterized protein.
   
 
 0.907
GBE
Eye-globin; Belongs to the globin family.
     
0.902
HBE
Hemoglobin subunit epsilon; Beta-type chain found in early embryos; Belongs to the globin family.
  
  
0.901
BCL11A
Uncharacterized protein.
      
 0.720
APOA1
Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.
   
 0.660
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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