STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG1Pleckstrin homology and RhoGEF domain containing G1. (1586 aa)    
Predicted Functional Partners:
IYD
Iodotyrosine deiodinase.
      
 0.775
STK32A
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
      
 0.756
C1QTNF4
C1q and TNF related 4.
      
 0.702
GPR149
Probable G-protein coupled receptor 149; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.699
DYNC1LI2
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
   
  
 0.649
GULP1
GULP PTB domain containing engulfment adaptor 1.
      
 0.648
NOS1AP
PID domain-containing protein.
      
 0.630
LOC417113
PID domain-containing protein.
      
 0.630
MPPED2
Metallophos domain-containing protein.
      
 0.593
CNTN5
Contactin-5; Contactins mediate cell surface interactions during nervous system development. May contribute to the formation of somatotopic maps of cerebellar afferents during the development of the nervous system. Belongs to the immunoglobulin superfamily. Contactin family.
      
 0.557
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.