node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD36 | CD47 | ENSGALP00000068876 | ENSGALP00000029799 | Uncharacterized protein; Belongs to the CD36 family. | CD47 glycoprotein isoform A. | 0.881 |
CD36 | ITGA2B | ENSGALP00000068876 | ENSGALP00000067023 | Uncharacterized protein; Belongs to the CD36 family. | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | 0.600 |
CD36 | ITGAV | ENSGALP00000068876 | ENSGALP00000047574 | Uncharacterized protein; Belongs to the CD36 family. | Integrin alpha-V heavy chain; The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase- 2, osteopontin, osteomodulin, prothrombin, thrombospondin, TGFB1 and vWF. They recognize the sequence R-G-D in a wide array of ligands. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing (By similarity). ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential [...] | 0.723 |
CD36 | ITGB3 | ENSGALP00000068876 | ENSGALP00000000518 | Uncharacterized protein; Belongs to the CD36 family. | Integrin beta; Belongs to the integrin beta chain family. | 0.625 |
CD36 | ITGB5 | ENSGALP00000068876 | ENSGALP00000047825 | Uncharacterized protein; Belongs to the CD36 family. | Integrin beta; Belongs to the integrin beta chain family. | 0.484 |
CD36 | THBS2 | ENSGALP00000068876 | ENSGALP00000073192 | Uncharacterized protein; Belongs to the CD36 family. | Thrombospondin-2; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions; Belongs to the thrombospondin family. | 0.987 |
CD47 | CD36 | ENSGALP00000029799 | ENSGALP00000068876 | CD47 glycoprotein isoform A. | Uncharacterized protein; Belongs to the CD36 family. | 0.881 |
CD47 | ITGAV | ENSGALP00000029799 | ENSGALP00000047574 | CD47 glycoprotein isoform A. | Integrin alpha-V heavy chain; The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase- 2, osteopontin, osteomodulin, prothrombin, thrombospondin, TGFB1 and vWF. They recognize the sequence R-G-D in a wide array of ligands. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing (By similarity). ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential [...] | 0.629 |
CD47 | ITGB3 | ENSGALP00000029799 | ENSGALP00000000518 | CD47 glycoprotein isoform A. | Integrin beta; Belongs to the integrin beta chain family. | 0.726 |
CD47 | THBS2 | ENSGALP00000029799 | ENSGALP00000073192 | CD47 glycoprotein isoform A. | Thrombospondin-2; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions; Belongs to the thrombospondin family. | 0.956 |
ITGA2B | CD36 | ENSGALP00000067023 | ENSGALP00000068876 | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | Uncharacterized protein; Belongs to the CD36 family. | 0.600 |
ITGA2B | ITGA8 | ENSGALP00000067023 | ENSGALP00000065785 | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | Integrin alpha-8 heavy chain; Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1, TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis (By similarity). Neuronal receptor for TNC it mediates cell- cell interactions and regulates neurite outgrowth of sensory and motor neurons. | 0.555 |
ITGA2B | ITGAV | ENSGALP00000067023 | ENSGALP00000047574 | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | Integrin alpha-V heavy chain; The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase- 2, osteopontin, osteomodulin, prothrombin, thrombospondin, TGFB1 and vWF. They recognize the sequence R-G-D in a wide array of ligands. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing (By similarity). ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential [...] | 0.588 |
ITGA2B | ITGB1 | ENSGALP00000067023 | ENSGALP00000054354 | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-1 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.683 |
ITGA2B | ITGB3 | ENSGALP00000067023 | ENSGALP00000000518 | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | Integrin beta; Belongs to the integrin beta chain family. | 0.982 |
ITGA2B | ITGB5 | ENSGALP00000067023 | ENSGALP00000047825 | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | Integrin beta; Belongs to the integrin beta chain family. | 0.720 |
ITGA2B | THBS2 | ENSGALP00000067023 | ENSGALP00000073192 | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | Thrombospondin-2; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions; Belongs to the thrombospondin family. | 0.906 |
ITGA8 | ITGA2B | ENSGALP00000065785 | ENSGALP00000067023 | Integrin alpha-8 heavy chain; Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1, TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis (By similarity). Neuronal receptor for TNC it mediates cell- cell interactions and regulates neurite outgrowth of sensory and motor neurons. | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. | 0.555 |
ITGA8 | ITGAV | ENSGALP00000065785 | ENSGALP00000047574 | Integrin alpha-8 heavy chain; Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1, TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis (By similarity). Neuronal receptor for TNC it mediates cell- cell interactions and regulates neurite outgrowth of sensory and motor neurons. | Integrin alpha-V heavy chain; The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase- 2, osteopontin, osteomodulin, prothrombin, thrombospondin, TGFB1 and vWF. They recognize the sequence R-G-D in a wide array of ligands. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing (By similarity). ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential [...] | 0.599 |
ITGA8 | ITGB1 | ENSGALP00000065785 | ENSGALP00000054354 | Integrin alpha-8 heavy chain; Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1, TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis (By similarity). Neuronal receptor for TNC it mediates cell- cell interactions and regulates neurite outgrowth of sensory and motor neurons. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-1 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.966 |