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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BZW2Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. (419 aa)    
Predicted Functional Partners:
ANKMY2
Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia.
      
 0.871
POLR3G
Uncharacterized protein.
      
 0.841
SNX13
Uncharacterized protein.
      
 0.827
SMPDL3B
Acid sphingomyelinase-like phosphodiesterase.
      
 0.783
POLR2D
RPOL4c domain-containing protein.
   
  
 0.778
GNL3
G protein nucleolar 3.
   
  
 0.752
POLR3D
Uncharacterized protein.
      
 0.748
TSPAN13
Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family.
 
    
 0.675
LARP7
La ribonucleoprotein domain family member 7.
   
  
 0.635
CDK9
Cyclin-dependent kinase 9; Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P- TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity). Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
      
 0.424
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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