Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PON1Serum paraoxonase/arylesterase 2; The absence of paraoxonase activity in turkey and chicken blood and in turkey liver indicates that PON2, if expressed, does not hydrolyze paraoxon. (354 aa)    
Predicted Functional Partners:
MARS
Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.720
ASB4
Ankyrin repeat and SOCS box containing 4.
      
 0.700
MARS2
Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.676
VPS50
Syndetin; Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
      
 0.639
HEPACAM2
HEPACAM family member 2.
      
 0.637
PPP1R9A
Protein phosphatase 1 regulatory subunit 9A.
   
  
 0.614
CASD1
CAS1 domain containing 1.
      
 0.611
SGCE
Sarcoglycan epsilon.
      
 0.561
ICA1
Islet cell autoantigen 1.
      
 0.550
C1GALT1
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
      
 0.509
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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