Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM59Tripartite motif-containing protein 59; May serve as a multifunctional regulator for innate immune signaling pathways. (408 aa)    
Predicted Functional Partners:
IFT81
IFT81_CH domain-containing protein.
   
 
 0.904
IFT74
Intraflagellar transport 74.
    
  0.901
TTC30B
TPR_REGION domain-containing protein.
     
  0.900
IFT57
Intraflagellar transport 57.
     
  0.900
IFT172
Intraflagellar transport 172.
     
  0.900
HSPB11
F5/8 type C domain-containing protein.
     
  0.900
IFT46
Intraflagellar transport 46.
     
  0.900
IFT80
Intraflagellar transport 80.
 
 
 
 0.764
TRIM8
RING-type domain-containing protein.
      
 0.721
TRIM23
Tripartite motif containing 23.
    
 
 0.655
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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