node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | FLNA | ENSGALP00000060844 | ENSGALP00000067245 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Uncharacterized protein. | 0.997 |
ACTB | FLNB | ENSGALP00000060844 | ENSGALP00000045421 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Uncharacterized protein. | 0.997 |
ACTB | ITGB2 | ENSGALP00000060844 | ENSGALP00000012130 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Integrin beta. | 0.752 |
ACTB | ITGB3 | ENSGALP00000060844 | ENSGALP00000000518 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Integrin beta; Belongs to the integrin beta chain family. | 0.767 |
ACTB | ITGB5 | ENSGALP00000060844 | ENSGALP00000047825 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Integrin beta; Belongs to the integrin beta chain family. | 0.716 |
ACTB | ITGB6 | ENSGALP00000060844 | ENSGALP00000018148 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Integrin beta; Belongs to the integrin beta chain family. | 0.723 |
ACTB | ITGB7 | ENSGALP00000060844 | ENSGALP00000074187 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Integrin beta; Belongs to the integrin beta chain family. | 0.710 |
ACTB | ITGB8 | ENSGALP00000060844 | ENSGALP00000058544 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Integrin beta; Belongs to the integrin beta chain family. | 0.703 |
ACTB | TLN1 | ENSGALP00000060844 | ENSGALP00000056315 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Talin-1; Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. | 0.997 |
ACTB | VCL | ENSGALP00000060844 | ENSGALP00000008131 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. | 0.999 |
FLNA | ACTB | ENSGALP00000067245 | ENSGALP00000060844 | Uncharacterized protein. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.997 |
FLNA | FLNB | ENSGALP00000067245 | ENSGALP00000045421 | Uncharacterized protein. | Uncharacterized protein. | 0.904 |
FLNA | ITGB2 | ENSGALP00000067245 | ENSGALP00000012130 | Uncharacterized protein. | Integrin beta. | 0.781 |
FLNA | ITGB3 | ENSGALP00000067245 | ENSGALP00000000518 | Uncharacterized protein. | Integrin beta; Belongs to the integrin beta chain family. | 0.940 |
FLNA | ITGB5 | ENSGALP00000067245 | ENSGALP00000047825 | Uncharacterized protein. | Integrin beta; Belongs to the integrin beta chain family. | 0.921 |
FLNA | ITGB6 | ENSGALP00000067245 | ENSGALP00000018148 | Uncharacterized protein. | Integrin beta; Belongs to the integrin beta chain family. | 0.921 |
FLNA | ITGB7 | ENSGALP00000067245 | ENSGALP00000074187 | Uncharacterized protein. | Integrin beta; Belongs to the integrin beta chain family. | 0.817 |
FLNA | ITGB8 | ENSGALP00000067245 | ENSGALP00000058544 | Uncharacterized protein. | Integrin beta; Belongs to the integrin beta chain family. | 0.917 |
FLNA | TLN1 | ENSGALP00000067245 | ENSGALP00000056315 | Uncharacterized protein. | Talin-1; Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. | 0.974 |
FLNA | VCL | ENSGALP00000067245 | ENSGALP00000008131 | Uncharacterized protein. | Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. | 0.968 |