node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADSS | ADSS1 | ENSGALP00000017386 | ENSGALP00000018960 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.918 |
ADSS | ASL1 | ENSGALP00000017386 | ENSGALP00000039143 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.523 |
ADSS | ASL2 | ENSGALP00000017386 | ENSGALP00000058708 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Argininosuccinate lyase; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles. This protein may also function as an enzymatically active argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.564 |
ADSS | ASNS | ENSGALP00000017386 | ENSGALP00000015846 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.935 |
ADSS | ASS1 | ENSGALP00000017386 | ENSGALP00000038774 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.960 |
ADSS | CPS1 | ENSGALP00000017386 | ENSGALP00000004647 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.507 |
ADSS | OAT | ENSGALP00000017386 | ENSGALP00000053373 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.578 |
ADSS1 | ADSS | ENSGALP00000018960 | ENSGALP00000017386 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | 0.918 |
ADSS1 | ASL1 | ENSGALP00000018960 | ENSGALP00000039143 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.523 |
ADSS1 | ASL2 | ENSGALP00000018960 | ENSGALP00000058708 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Argininosuccinate lyase; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles. This protein may also function as an enzymatically active argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.523 |
ADSS1 | ASNS | ENSGALP00000018960 | ENSGALP00000015846 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.933 |
ADSS1 | ASS1 | ENSGALP00000018960 | ENSGALP00000038774 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.956 |
ADSS1 | CPS1 | ENSGALP00000018960 | ENSGALP00000004647 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.505 |
ADSS1 | OAT | ENSGALP00000018960 | ENSGALP00000053373 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.578 |
ASL1 | ADSS | ENSGALP00000039143 | ENSGALP00000017386 | Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | 0.523 |
ASL1 | ADSS1 | ENSGALP00000039143 | ENSGALP00000018960 | Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.523 |
ASL1 | ASS1 | ENSGALP00000039143 | ENSGALP00000038774 | Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.994 |
ASL1 | CPS1 | ENSGALP00000039143 | ENSGALP00000004647 | Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Uncharacterized protein. | 0.688 |
ASL1 | OAT | ENSGALP00000039143 | ENSGALP00000053373 | Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.987 |
ASL1 | OTC | ENSGALP00000039143 | ENSGALP00000026160 | Delta-1 crystallin; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Ornithine carbamoyltransferase, mitochondrial. | 0.811 |