FNIP1 protein (Gallus gallus) - STRING interaction network

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FNIP1

Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family. (1170 aa)

Predicted Functional Partners:

FLCN

0.989

FNIP2

0.958

RRAGB

0.921

RRAGD

0.914

RRAGC

0.914

FEM1B

0.870

SIL1

0.675

TMEM59L

0.643

TMEM59

0.643

HSPA8

0.643

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEM1B	FNIP1	ENSGALP00000042401	ENSGALP00000058436	Protein fem-1 homolog B; Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis (By similarity); Belongs to the fem-1 family.	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	0.870
FLCN	FNIP1	ENSGALP00000047085	ENSGALP00000058436	UDENN FLCN/SMCR8-type domain-containing protein.	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	0.989
FLCN	FNIP2	ENSGALP00000047085	ENSGALP00000066761	UDENN FLCN/SMCR8-type domain-containing protein.	Folliculin interacting protein 2.	0.999
FLCN	RRAGB	ENSGALP00000047085	ENSGALP00000073101	UDENN FLCN/SMCR8-type domain-containing protein.	Ras related GTP binding B.	0.989
FLCN	RRAGC	ENSGALP00000047085	ENSGALP00000053707	UDENN FLCN/SMCR8-type domain-containing protein.	Uncharacterized protein.	0.976
FLCN	RRAGD	ENSGALP00000047085	ENSGALP00000042542	UDENN FLCN/SMCR8-type domain-containing protein.	Ras related GTP binding D.	0.976
FNIP1	FEM1B	ENSGALP00000058436	ENSGALP00000042401	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	Protein fem-1 homolog B; Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis (By similarity); Belongs to the fem-1 family.	0.870
FNIP1	FLCN	ENSGALP00000058436	ENSGALP00000047085	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	UDENN FLCN/SMCR8-type domain-containing protein.	0.989
FNIP1	FNIP2	ENSGALP00000058436	ENSGALP00000066761	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	Folliculin interacting protein 2.	0.958
FNIP1	HSPA8	ENSGALP00000058436	ENSGALP00000051563	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]	0.643
FNIP1	RRAGB	ENSGALP00000058436	ENSGALP00000073101	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	Ras related GTP binding B.	0.921
FNIP1	RRAGC	ENSGALP00000058436	ENSGALP00000053707	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	Uncharacterized protein.	0.914
FNIP1	RRAGD	ENSGALP00000058436	ENSGALP00000042542	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	Ras related GTP binding D.	0.914
FNIP1	SIL1	ENSGALP00000058436	ENSGALP00000072140	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	SIL1 nucleotide exchange factor.	0.675
FNIP1	TMEM59	ENSGALP00000058436	ENSGALP00000044651	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	Uncharacterized protein.	0.643
FNIP1	TMEM59L	ENSGALP00000058436	ENSGALP00000034392	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	Transmembrane protein 59 like.	0.643
FNIP2	FLCN	ENSGALP00000066761	ENSGALP00000047085	Folliculin interacting protein 2.	UDENN FLCN/SMCR8-type domain-containing protein.	0.999
FNIP2	FNIP1	ENSGALP00000066761	ENSGALP00000058436	Folliculin interacting protein 2.	Folliculin-interacting protein 1; May act as a co-chaperone of HSP90AA1. May inhibit the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. May be involved in energy and/or nutrient sensing. Belongs to the FNIP family.	0.958
FNIP2	RRAGB	ENSGALP00000066761	ENSGALP00000073101	Folliculin interacting protein 2.	Ras related GTP binding B.	0.965
FNIP2	RRAGC	ENSGALP00000066761	ENSGALP00000053707	Folliculin interacting protein 2.	Uncharacterized protein.	0.961

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