| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | APIP | ENSGALP00000053552 | ENSGALP00000054200 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. | 0.506 |
| ALDH18A1 | RIC8A | ENSGALP00000053552 | ENSGALP00000071454 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | 0.630 |
| APIP | ALDH18A1 | ENSGALP00000054200 | ENSGALP00000053552 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.506 |
| APIP | IGHMBP2 | ENSGALP00000054200 | ENSGALP00000006890 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. | Uncharacterized protein. | 0.705 |
| APIP | RIC8A | ENSGALP00000054200 | ENSGALP00000071454 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | 0.665 |
| APIP | ZDHHC13 | ENSGALP00000054200 | ENSGALP00000045719 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. | 0.742 |
| GNA11 | GNAQ | ENSGALP00000005115 | ENSGALP00000024446 | Guanine nucleotide-binding protein G11 alpha-subunit. | Uncharacterized protein. | 0.902 |
| GNA11 | RIC8A | ENSGALP00000005115 | ENSGALP00000071454 | Guanine nucleotide-binding protein G11 alpha-subunit. | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | 0.729 |
| GNAQ | GNA11 | ENSGALP00000024446 | ENSGALP00000005115 | Uncharacterized protein. | Guanine nucleotide-binding protein G11 alpha-subunit. | 0.902 |
| GNAQ | RIC8A | ENSGALP00000024446 | ENSGALP00000071454 | Uncharacterized protein. | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | 0.714 |
| IGHMBP2 | APIP | ENSGALP00000006890 | ENSGALP00000054200 | Uncharacterized protein. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. | 0.705 |
| IGHMBP2 | RIC8A | ENSGALP00000006890 | ENSGALP00000071454 | Uncharacterized protein. | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | 0.627 |
| IGHMBP2 | ZDHHC13 | ENSGALP00000006890 | ENSGALP00000045719 | Uncharacterized protein. | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. | 0.740 |
| MISP | RIC8A | ENSGALP00000069154 | ENSGALP00000071454 | Uncharacterized protein. | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | 0.704 |
| MISP | SAPCD2 | ENSGALP00000069154 | ENSGALP00000072014 | Uncharacterized protein. | Suppressor APC domain containing 2. | 0.955 |
| RABIF | RIC8A | ENSGALP00000000592 | ENSGALP00000071454 | RAB interacting factor. | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | 0.671 |
| RIC8A | ALDH18A1 | ENSGALP00000071454 | ENSGALP00000053552 | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.630 |
| RIC8A | APIP | ENSGALP00000071454 | ENSGALP00000054200 | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. | 0.665 |
| RIC8A | GNA11 | ENSGALP00000071454 | ENSGALP00000005115 | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | Guanine nucleotide-binding protein G11 alpha-subunit. | 0.729 |
| RIC8A | GNAQ | ENSGALP00000071454 | ENSGALP00000024446 | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). | Uncharacterized protein. | 0.714 |