Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
MBL2Mannose-binding protein; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. (254 aa)    
Predicted Functional Partners:
MASP2
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.965
C1R
Complement C1r; Belongs to the peptidase S1 family.
   
 0.910
LGALS3
Galectin.
   
 
 0.910
CFI
Uncharacterized protein; Belongs to the peptidase S1 family.
   
  
 0.880
SFTPC
BRICHOS domain-containing protein.
   
  
 0.878
FCN2
Fibrinogen C-terminal domain-containing protein.
    
 
 0.861
C1S
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 
 0.850
LOC425940
Uncharacterized protein.
   
  
 0.841
FGG
Fibrinogen C-terminal domain-containing protein.
   
 
 0.746
ORM1
Alpha-1-acid glycoprotein; Functions as transport protein in the blood stream. Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.742
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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