CMPK1 protein (Gallus gallus) - STRING interaction network

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CMPK1

UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (196 aa)

Predicted Functional Partners:

CMPK2

0.982

UMPS

0.967

UCK2

0.964

NME4

0.959

RRM1

0.956

UCK1

0.954

RRM2

0.950

DCTD

0.948

DCK

0.948

NME7

0.946

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMPK1	CMPK2	ENSGALP00000017049	ENSGALP00000042236	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Cytidine/uridine monophosphate kinase 2.	0.982
CMPK1	DCK	ENSGALP00000017049	ENSGALP00000042484	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	dNK domain-containing protein.	0.948
CMPK1	DCTD	ENSGALP00000017049	ENSGALP00000017346	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	CMP/dCMP-type deaminase domain-containing protein.	0.948
CMPK1	NME4	ENSGALP00000017049	ENSGALP00000004225	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase.	0.959
CMPK1	NME7	ENSGALP00000017049	ENSGALP00000068515	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.946
CMPK1	RRM1	ENSGALP00000017049	ENSGALP00000027981	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.956
CMPK1	RRM2	ENSGALP00000017049	ENSGALP00000026474	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ribonucleotide reductase regulatory subunit M2.	0.950
CMPK1	UCK1	ENSGALP00000017049	ENSGALP00000005911	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.954
CMPK1	UCK2	ENSGALP00000017049	ENSGALP00000005542	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.964
CMPK1	UMPS	ENSGALP00000017049	ENSGALP00000019192	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	OMPdecase domain-containing protein.	0.967
CMPK2	CMPK1	ENSGALP00000042236	ENSGALP00000017049	Cytidine/uridine monophosphate kinase 2.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.982
CMPK2	DCK	ENSGALP00000042236	ENSGALP00000042484	Cytidine/uridine monophosphate kinase 2.	dNK domain-containing protein.	0.936
CMPK2	DCTD	ENSGALP00000042236	ENSGALP00000017346	Cytidine/uridine monophosphate kinase 2.	CMP/dCMP-type deaminase domain-containing protein.	0.950
CMPK2	NME4	ENSGALP00000042236	ENSGALP00000004225	Cytidine/uridine monophosphate kinase 2.	Nucleoside diphosphate kinase.	0.962
CMPK2	NME7	ENSGALP00000042236	ENSGALP00000068515	Cytidine/uridine monophosphate kinase 2.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.943
CMPK2	RRM1	ENSGALP00000042236	ENSGALP00000027981	Cytidine/uridine monophosphate kinase 2.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.951
CMPK2	RRM2	ENSGALP00000042236	ENSGALP00000026474	Cytidine/uridine monophosphate kinase 2.	Ribonucleotide reductase regulatory subunit M2.	0.918
CMPK2	UCK1	ENSGALP00000042236	ENSGALP00000005911	Cytidine/uridine monophosphate kinase 2.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.913
CMPK2	UCK2	ENSGALP00000042236	ENSGALP00000005542	Cytidine/uridine monophosphate kinase 2.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.913
CMPK2	UMPS	ENSGALP00000042236	ENSGALP00000019192	Cytidine/uridine monophosphate kinase 2.	OMPdecase domain-containing protein.	0.945

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