STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XPNPEP2X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family. (681 aa)    
Predicted Functional Partners:
XPNPEP3
X-prolyl aminopeptidase 3.
      
 0.812
NME4
Nucleoside diphosphate kinase.
   
  
 0.783
EVA1B
Eva-1 homolog B.
   
  
 0.748
MEP1A
Meprin A subunit.
   
  
 0.726
BLMH
Bleomycin hydrolase; The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity; Belongs to the peptidase C1 family.
  
  
 0.724
PEPD
AMP_N domain-containing protein.
      
 0.724
DNPEP
Uncharacterized protein; Belongs to the peptidase M18 family.
   
 
 0.715
ATP1B4
Protein ATP1B4; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.
   
  
 0.706
LVRN
Aminopeptidase.
  
 
 0.695
NPEPPS
Aminopeptidase puromycin sensitive.
  
 
 0.695
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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