STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS1DIRAS family GTPase 1. (198 aa)    
Predicted Functional Partners:
ELMO1
ELMO domain-containing protein.
    
 
 0.657
ITSN2
Intersectin 2.
    
 
 0.648
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 
 0.642
ITSN1
Intersectin 1.
    
 
 0.578
ARL4A
ADP ribosylation factor like GTPase 4A.
   
 
 0.551
ENSGALP00000070136
Uncharacterized protein.
    
 
 0.548
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 
 0.467
NF1
Neurofibromin; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.
    
 
 0.463
ENSGALP00000070239
Uncharacterized protein.
   
 
 0.458
ENSGALP00000072617
Uncharacterized protein.
   
 
 0.458
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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