node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DLX5 | DLX6 | ENSGALP00000014846 | ENSGALP00000069962 | Homeobox protein DLX-5; Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA; Belongs to the distal-less homeobox family. | Homeobox domain-containing protein. | 0.752 |
DLX5 | EYA1 | ENSGALP00000014846 | ENSGALP00000051963 | Homeobox protein DLX-5; Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA; Belongs to the distal-less homeobox family. | Eyes absent homolog 1; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function i [...] | 0.721 |
DLX5 | FOXI3 | ENSGALP00000014846 | ENSGALP00000043843 | Homeobox protein DLX-5; Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA; Belongs to the distal-less homeobox family. | Fork-head domain-containing protein. | 0.534 |
DLX5 | PAX2 | ENSGALP00000014846 | ENSGALP00000045193 | Homeobox protein DLX-5; Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA; Belongs to the distal-less homeobox family. | Paired-box containing protein Pax-2. | 0.710 |
DLX5 | SIX1 | ENSGALP00000014846 | ENSGALP00000046244 | Homeobox protein DLX-5; Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA; Belongs to the distal-less homeobox family. | Sine oculis-related homeobox 1 homolog. | 0.784 |
DLX6 | DLX5 | ENSGALP00000069962 | ENSGALP00000014846 | Homeobox domain-containing protein. | Homeobox protein DLX-5; Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA; Belongs to the distal-less homeobox family. | 0.752 |
DLX6 | FOXI3 | ENSGALP00000069962 | ENSGALP00000043843 | Homeobox domain-containing protein. | Fork-head domain-containing protein. | 0.502 |
DLX6 | SIX1 | ENSGALP00000069962 | ENSGALP00000046244 | Homeobox domain-containing protein. | Sine oculis-related homeobox 1 homolog. | 0.432 |
EYA1 | DLX5 | ENSGALP00000051963 | ENSGALP00000014846 | Eyes absent homolog 1; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function i [...] | Homeobox protein DLX-5; Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA; Belongs to the distal-less homeobox family. | 0.721 |
EYA1 | FOXI3 | ENSGALP00000051963 | ENSGALP00000043843 | Eyes absent homolog 1; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function i [...] | Fork-head domain-containing protein. | 0.481 |
EYA1 | PAX2 | ENSGALP00000051963 | ENSGALP00000045193 | Eyes absent homolog 1; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function i [...] | Paired-box containing protein Pax-2. | 0.868 |
EYA1 | PAX9 | ENSGALP00000051963 | ENSGALP00000037011 | Eyes absent homolog 1; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function i [...] | Paired box protein Pax-9. | 0.420 |
EYA1 | SIX1 | ENSGALP00000051963 | ENSGALP00000046244 | Eyes absent homolog 1; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function i [...] | Sine oculis-related homeobox 1 homolog. | 0.993 |
FOXI3 | DLX5 | ENSGALP00000043843 | ENSGALP00000014846 | Fork-head domain-containing protein. | Homeobox protein DLX-5; Transcriptional factor involved in bone development. Could be involved in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Binds to DNA; Belongs to the distal-less homeobox family. | 0.534 |
FOXI3 | DLX6 | ENSGALP00000043843 | ENSGALP00000069962 | Fork-head domain-containing protein. | Homeobox domain-containing protein. | 0.502 |
FOXI3 | EYA1 | ENSGALP00000043843 | ENSGALP00000051963 | Fork-head domain-containing protein. | Eyes absent homolog 1; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function i [...] | 0.481 |
FOXI3 | GCM2 | ENSGALP00000043843 | ENSGALP00000020805 | Fork-head domain-containing protein. | GCM domain-containing protein. | 0.601 |
FOXI3 | LOC776719 | ENSGALP00000043843 | ENSGALP00000056523 | Fork-head domain-containing protein. | Uncharacterized protein. | 0.688 |
FOXI3 | PAX2 | ENSGALP00000043843 | ENSGALP00000045193 | Fork-head domain-containing protein. | Paired-box containing protein Pax-2. | 0.529 |
FOXI3 | PAX9 | ENSGALP00000043843 | ENSGALP00000037011 | Fork-head domain-containing protein. | Paired box protein Pax-9. | 0.499 |