STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADGRL3Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1519 aa)    
Predicted Functional Partners:
UNC5D
Unc-5 netrin receptor D.
   
 
 0.989
UNC5A
Unc-5 netrin receptor A.
   
 
 0.988
UNC5C
Netrin receptor UNC5C; Receptor for netrin required for axon guidance (By similarity). Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord.
   
 
 0.988
FRMD1
FERM domain-containing protein.
    
   0.987
GNB1
WD_REPEATS_REGION domain-containing protein.
   
   0.987
GNB5
WD_REPEATS_REGION domain-containing protein.
   
   0.987
GNB3
G protein subunit beta 3.
   
   0.987
GNB4
G protein subunit beta 4.
   
   0.987
FRMD6
FERM domain containing 6.
    
   0.987
FLRT3
Leucine-rich repeat transmembrane protein FLRT3; Modulates the structure and function of the apical ectodermal ridge (AER) that controls embryonic limb development. Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development. Plays a role in cell-cell adhesion via its interaction with latrophilins that are expressed at the surface of adjacent cells. Mediates axon attraction towards cells expressing NTN1. M [...]
    
 
 0.981
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.