STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX1-1NK1 homeobox 1. (369 aa)    
Predicted Functional Partners:
LAMTOR5
Uncharacterized protein.
      
 0.476
POU6F1
POU domain protein.
      
 0.467
FOXS1
Forkhead box S1.
    
 
 0.445
POU2F3
POU domain protein.
      
 0.436
IRX4
Iroquois-class homeodomain protein IRX-4; Regulates the chamber-specific expression of myosin isoforms by activating the expression of the ventricle myosin heavy chain-1 (Vmhc1) and suppressing the expression of the atrial myosin heavy chain-1 (Amhc1) in the ventricles. May play a critical role in establishing chamber-specific gene expression in the developing heart; Belongs to the TALE/IRO homeobox family.
   
 
 0.432
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.