Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FAM217B | TEAD3 | ENSGALP00000042571 | ENSGALP00000046990 | Family with sequence similarity 217 member B. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | 0.706 |
| GOLT1A | PPFIA4 | ENSGALP00000068701 | ENSGALP00000000286 | Golgi transport 1A. | PTPRF interacting protein alpha 4. | 0.863 |
| GOLT1A | TEAD3 | ENSGALP00000068701 | ENSGALP00000046990 | Golgi transport 1A. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | 0.745 |
| INSM2 | TEAD3 | ENSGALP00000068474 | ENSGALP00000046990 | INSM transcriptional repressor 2. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | 0.641 |
| LATS1 | SAV1 | ENSGALP00000020194 | ENSGALP00000020137 | Large tumor suppressor kinase 1. | Salvador family WW domain containing protein 1. | 0.989 |
| LATS1 | TEAD3 | ENSGALP00000020194 | ENSGALP00000046990 | Large tumor suppressor kinase 1. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | 0.643 |
| LATS1 | VGLL4 | ENSGALP00000020194 | ENSGALP00000007888 | Large tumor suppressor kinase 1. | Uncharacterized protein. | 0.710 |
| LATS1 | WWTR1 | ENSGALP00000020194 | ENSGALP00000016933 | Large tumor suppressor kinase 1. | WW domain containing transcription regulator 1. | 0.913 |
| LATS1 | YAP1 | ENSGALP00000020194 | ENSGALP00000053936 | Large tumor suppressor kinase 1. | Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation (By similarity); Belongs to the YAP1 family. | 0.961 |
| PPFIA4 | GOLT1A | ENSGALP00000000286 | ENSGALP00000068701 | PTPRF interacting protein alpha 4. | Golgi transport 1A. | 0.863 |
| PPFIA4 | TEAD3 | ENSGALP00000000286 | ENSGALP00000046990 | PTPRF interacting protein alpha 4. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | 0.768 |
| SAV1 | LATS1 | ENSGALP00000020137 | ENSGALP00000020194 | Salvador family WW domain containing protein 1. | Large tumor suppressor kinase 1. | 0.989 |
| SAV1 | TEAD3 | ENSGALP00000020137 | ENSGALP00000046990 | Salvador family WW domain containing protein 1. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | 0.678 |
| SAV1 | VGLL4 | ENSGALP00000020137 | ENSGALP00000007888 | Salvador family WW domain containing protein 1. | Uncharacterized protein. | 0.755 |
| SAV1 | WWTR1 | ENSGALP00000020137 | ENSGALP00000016933 | Salvador family WW domain containing protein 1. | WW domain containing transcription regulator 1. | 0.843 |
| SAV1 | YAP1 | ENSGALP00000020137 | ENSGALP00000053936 | Salvador family WW domain containing protein 1. | Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation (By similarity); Belongs to the YAP1 family. | 0.778 |
| TEAD3 | FAM217B | ENSGALP00000046990 | ENSGALP00000042571 | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | Family with sequence similarity 217 member B. | 0.706 |
| TEAD3 | GOLT1A | ENSGALP00000046990 | ENSGALP00000068701 | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | Golgi transport 1A. | 0.745 |
| TEAD3 | INSM2 | ENSGALP00000046990 | ENSGALP00000068474 | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | INSM transcriptional repressor 2. | 0.641 |
| TEAD3 | LATS1 | ENSGALP00000046990 | ENSGALP00000020194 | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ (By similarity). | Large tumor suppressor kinase 1. | 0.643 |
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