STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BEST4Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (488 aa)    
Predicted Functional Partners:
TNFRSF14
Death domain-containing protein.
      
 0.742
SLC13A2
Solute carrier family 13 member 2.
      
 0.703
OTOP2
Otopetrin 2.
      
 0.670
TPCN3
Uncharacterized protein.
      
 0.629
RPL27A
Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family.
      
 0.587
CABIN1
Calcineurin binding protein 1.
      
 0.583
CA7
Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family.
      
 0.537
RPS29
Uncharacterized protein.
   
  
 0.510
CLCA1
Chloride channel accessory 1.
      
 0.507
ATP6V0A4
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
    
 
 0.501
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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