STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LTA4HLeukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (680 aa)    
Predicted Functional Partners:
LTC4SL
Uncharacterized protein.
     
 0.970
ALOX5
Arachidonate 5-lipoxygenase.
     
 0.915
TRIT1
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.
 
      0.884
LTC4S
Uncharacterized protein.
      
 0.745
ALOX5AP
Uncharacterized protein.
   
  
 0.679
SUOX
Sulfite oxidase.
      
 0.629
PLA2G4A
Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
    
 
 0.606
PTGR1
PKS_ER domain-containing protein.
   
  
 0.602
TBXAS1
Thromboxane A synthase 1; Belongs to the cytochrome P450 family.
    
 
 0.588
CNDP2
M20_dimer domain-containing protein.
 
 
 0.585
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.