Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
UBAC2Ubiquitin-associated domain-containing protein 2; Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets (By similarity). May negatively regulate the canonical Wnt signaling pathway in the lymphocytes (By similarity). (344 aa)    
Predicted Functional Partners:
FAF2
Fas associated factor family member 2.
    
 
 0.964
UFD1L
Ubiquitin fusion-degradation 1-like protein.
    
 
 0.946
RHBDL1
Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
   
  
 0.923
EMC3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
   
 
 0.887
EMC1
ER membrane protein complex subunit 1; Belongs to the EMC1 family.
    
 
 0.874
EMC2
TPR_REGION domain-containing protein.
    
 
 0.842
AMFR
Autocrine motility factor receptor.
    
 
 0.799
ENSGALP00000054501
Uncharacterized protein.
    
 
 0.799
TMEM43
Transmembrane protein 43.
    
 
 0.796
FAF1
Fas associated factor 1.
    
 
 0.794
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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