STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCB1ATP binding cassette subfamily B member 1. (1293 aa)    
Predicted Functional Partners:
CYP3A4
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
  
 0.634
RUNDC3B
RUN domain-containing protein.
   
  
 0.554
ABCC2
Uncharacterized protein.
   
 
0.553
ABCC1
Multidrug resistance-associated protein 1; Mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
   
 
0.549
COMTD1
Catechol-O-methyltransferase domain containing 1.
   
  
 0.530
CYP2C23a
Cytochrome P450 2H1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
   
 
 0.501
ABCG2
ATP-binding cassette sub-family G member 2.
 
 
0.491
CYP3A5
Uncharacterized protein.
   
  
 0.489
ABCA13
Uncharacterized protein.
  
 
 0.467
ABCC5
ATP binding cassette subfamily C member 5.
   
 
0.452
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.