STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHANK2SH3 and multiple ankyrin repeat domains 2. (1462 aa)    
Predicted Functional Partners:
ENSGALP00000070136
Uncharacterized protein.
 
  
   0.903
DLGAP1
DLG associated protein 1.
    
 0.897
DLGAP2
DLG associated protein 2.
    
 0.810
DLGAP3
DLG associated protein 3.
    
 0.737
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
   
 0.727
CTTN
Src substrate protein p85; Contributes to the organization of the actin cytoskeleton and cell shape (By similarity). Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones, and may play a role in the regulation of neuronal spine density (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cel [...]
    
 
 0.718
HCLS1
SH3 domain-containing protein.
    
 
 0.709
NLGN1
Neuroligin 1 isoform A1A2B.
     
 0.694
DLGAP4
DLG associated protein 4.
    
 0.689
NLGN2
Neuroligin 2.
     
 0.670
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.