STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (358 aa)    
Predicted Functional Partners:
CCL5
C-C motif chemokine.
    
 0.973
CCL17
C-C motif chemokine.
     
 0.969
CCL4-2
C-C motif chemokine 4 homolog; Monokine with inflammatory and chemokinetic properties.
   
 0.718
STRAP
Serine-threonine kinase receptor-associated protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. ST [...]
      
 0.707
CXCL12
SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.701
CCL20
C-C motif chemokine.
    
 0.650
CCR7
C-C chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.
   
 
0.647
CCL4
C-C motif chemokine 4 homolog.
    
 0.638
CCL19
C-C motif chemokine.
   
 0.634
CCR8
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
  
0.627
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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