STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STXBP1Syntaxin-binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxins, components of the synaptic vesicle fusion machinery. May play a role in determining the specificity of intracellular fusion reactions (By similarity). Belongs to the STXBP/unc-18/SEC1 family. (603 aa)    
Predicted Functional Partners:
STX1A
Syntaxin 1A; Belongs to the syntaxin family.
   
 0.990
SNAP25
Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family.
   
 0.974
APBA1
Amyloid beta precursor protein binding family A member 1.
   
 
 0.914
LANCL1
Uncharacterized protein.
      
 0.840
STX3
Syntaxin 3; Belongs to the syntaxin family.
   
 
 0.828
STX11
Syntaxin 11.
   
 
 0.827
CPLX1
Complexin 1.
   
 
 0.826
VAMP2
V-SNARE coiled-coil homology domain-containing protein.
   
 
 0.825
STX2
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
   
 
 0.801
STX19
Syntaxin 19; Belongs to the syntaxin family.
   
 
 0.780
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.