ABL2 protein (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ABL2

Tyrosine-protein kinase. (1159 aa)

Predicted Functional Partners:

CRK

0.973

CRKL

0.964

ABL1

0.907

ABI1

0.848

AXDND1

0.742

ABI2

0.654

ENSGALP00000052573

0.643

XPR1

0.636

GRB2

0.634

RIOK1

0.617

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	ABI2	ENSGALP00000014164	ENSGALP00000056057	Uncharacterized protein.	Abl interactor 2.	0.556
ABI1	ABL1	ENSGALP00000014164	ENSGALP00000006154	Uncharacterized protein.	Tyrosine-protein kinase.	0.888
ABI1	ABL2	ENSGALP00000014164	ENSGALP00000052767	Uncharacterized protein.	Tyrosine-protein kinase.	0.848
ABI1	CRK	ENSGALP00000014164	ENSGALP00000004174	Uncharacterized protein.	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	0.697
ABI1	GRB2	ENSGALP00000014164	ENSGALP00000012993	Uncharacterized protein.	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	0.550
ABI2	ABI1	ENSGALP00000056057	ENSGALP00000014164	Abl interactor 2.	Uncharacterized protein.	0.556
ABI2	ABL1	ENSGALP00000056057	ENSGALP00000006154	Abl interactor 2.	Tyrosine-protein kinase.	0.775
ABI2	ABL2	ENSGALP00000056057	ENSGALP00000052767	Abl interactor 2.	Tyrosine-protein kinase.	0.654
ABI2	CRK	ENSGALP00000056057	ENSGALP00000004174	Abl interactor 2.	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	0.563
ABI2	GRB2	ENSGALP00000056057	ENSGALP00000012993	Abl interactor 2.	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	0.501
ABL1	ABI1	ENSGALP00000006154	ENSGALP00000014164	Tyrosine-protein kinase.	Uncharacterized protein.	0.888
ABL1	ABI2	ENSGALP00000006154	ENSGALP00000056057	Tyrosine-protein kinase.	Abl interactor 2.	0.775
ABL1	ABL2	ENSGALP00000006154	ENSGALP00000052767	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.907
ABL1	CRK	ENSGALP00000006154	ENSGALP00000004174	Tyrosine-protein kinase.	Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity).	0.974
ABL1	CRKL	ENSGALP00000006154	ENSGALP00000010305	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.971
ABL1	ENSGALP00000052573	ENSGALP00000006154	ENSGALP00000052573	Tyrosine-protein kinase.	tRNA-synt_1 domain-containing protein.	0.643
ABL1	GRB2	ENSGALP00000006154	ENSGALP00000012993	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	0.645
ABL1	RIOK1	ENSGALP00000006154	ENSGALP00000069087	Tyrosine-protein kinase.	RIO kinase 1.	0.451
ABL2	ABI1	ENSGALP00000052767	ENSGALP00000014164	Tyrosine-protein kinase.	Uncharacterized protein.	0.848
ABL2	ABI2	ENSGALP00000052767	ENSGALP00000056057	Tyrosine-protein kinase.	Abl interactor 2.	0.654