STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGALP00000052965Adaptin_N domain-containing protein. (250 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 
 0.988
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
 
     0.920
ITSN1
Intersectin 1.
    
 
 0.877
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
   
 
 0.779
AP1G1
AP-1 complex subunit gamma.
   
 
 0.767
AP2M1
AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP50 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositide- containing lipids (By similarity).
   
 
 0.765
AP2S1
Adaptor related protein complex 2 subunit sigma 1.
   
 
 0.738
AP4S1
Adaptor related protein complex 4 subunit sigma 1.
    
 
 0.722
CLTC
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 
 0.651
CLTCL1
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 
 0.651
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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