STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLITRK3SLIT and NTRK like family member 3. (886 aa)    
Predicted Functional Partners:
NLGN2
Neuroligin 2.
   
  
 0.904
PTPRS
Receptor-type tyrosine-protein phosphatase S; Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth (By similarity). Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for norm [...]
   
 
 0.822
PTPRD
Protein tyrosine phosphatase receptor type D.
   
 0.802
IL1RAPL1
Interleukin 1 receptor accessory protein like 1.
   
 
 0.777
D2HGDH
D-2-hydroxyglutarate dehydrogenase.
      
 0.728
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.708
NLGN1
Neuroligin 1 isoform A1A2B.
   
  
 0.705
LRRC2
Leucine rich repeat containing 2.
      
 0.702
ADGRL2
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.693
TRA2B
Transformer-2 beta.
    
 
 0.650
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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