STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1BPPM-type phosphatase domain-containing protein. (410 aa)    
Predicted Functional Partners:
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
  
 0.939
ABHD17C
Alpha/beta hydrolase domain-containing protein 17C; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS. Belongs to the AB hydrolase superfamily. ABHD17 family.
   
  
 0.708
TMEM68
Transmembrane protein 68.
   
  
 0.706
PREPL
Prolyl endopeptidase-like; Serine peptidase whose precise substrate specificity remains unclear (By similarity). Does not cleave peptides after a arginine or lysine residue (By similarity). Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex (By similarity). May play a role in the regulation of synaptic vesicle exocytosis (By similarity).
   
  
 0.698
GHRH
GHRH/PACAP-like.
   
    0.695
RIC8B
RIC8 guanine nucleotide exchange factor B.
   
  
 0.665
PPM1A
Protein phosphatase, Mg2+/Mn2+ dependent 1A.
  
 
0.651
LYPLA1
Lysophospholipase 1.
   
  
 0.588
SLC3A1
Solute carrier family 3 member 1.
 
 
  
 0.585
XKR4
XK-related protein.
      
 0.581
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.