node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASIC1 | LARP4 | ENSGALP00000073201 | ENSGALP00000045521 | Acid-sensing ion channel 1; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC1 subfamily. | HTH La-type RNA-binding domain-containing protein. | 0.745 |
ASIC1 | SLC48A1 | ENSGALP00000073201 | ENSGALP00000055141 | Acid-sensing ion channel 1; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC1 subfamily. | Heme transporter HRG1; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. Belongs to the HRG family. | 0.589 |
ASIC1 | TWIST3 | ENSGALP00000073201 | ENSGALP00000049630 | Acid-sensing ion channel 1; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC1 subfamily. | Twist3. | 0.675 |
GGA2 | LARP4 | ENSGALP00000009899 | ENSGALP00000045521 | Uncharacterized protein. | HTH La-type RNA-binding domain-containing protein. | 0.673 |
GGA2 | SLC48A1 | ENSGALP00000009899 | ENSGALP00000055141 | Uncharacterized protein. | Heme transporter HRG1; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. Belongs to the HRG family. | 0.478 |
GGA2 | TWIST3 | ENSGALP00000009899 | ENSGALP00000049630 | Uncharacterized protein. | Twist3. | 0.533 |
HDAC7 | LARP4 | ENSGALP00000067739 | ENSGALP00000045521 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | HTH La-type RNA-binding domain-containing protein. | 0.674 |
HDAC7 | RPAP3 | ENSGALP00000067739 | ENSGALP00000015837 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | RNA polymerase II-associated protein 3; May for an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein. | 0.502 |
HDAC7 | SLC48A1 | ENSGALP00000067739 | ENSGALP00000055141 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | Heme transporter HRG1; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. Belongs to the HRG family. | 0.600 |
HDAC7 | TMEM106C | ENSGALP00000067739 | ENSGALP00000060315 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | Transmembrane protein 106C. | 0.463 |
HDAC7 | TWIST3 | ENSGALP00000067739 | ENSGALP00000049630 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | Twist3. | 0.558 |
LARP4 | ASIC1 | ENSGALP00000045521 | ENSGALP00000073201 | HTH La-type RNA-binding domain-containing protein. | Acid-sensing ion channel 1; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC1 subfamily. | 0.745 |
LARP4 | GGA2 | ENSGALP00000045521 | ENSGALP00000009899 | HTH La-type RNA-binding domain-containing protein. | Uncharacterized protein. | 0.673 |
LARP4 | HDAC7 | ENSGALP00000045521 | ENSGALP00000067739 | HTH La-type RNA-binding domain-containing protein. | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | 0.674 |
LARP4 | SLC48A1 | ENSGALP00000045521 | ENSGALP00000055141 | HTH La-type RNA-binding domain-containing protein. | Heme transporter HRG1; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. Belongs to the HRG family. | 0.844 |
LARP4 | TWIST3 | ENSGALP00000045521 | ENSGALP00000049630 | HTH La-type RNA-binding domain-containing protein. | Twist3. | 0.850 |
RAPGEF3 | RPAP3 | ENSGALP00000068491 | ENSGALP00000015837 | Rap guanine nucleotide exchange factor 3. | RNA polymerase II-associated protein 3; May for an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein. | 0.764 |
RAPGEF3 | SLC48A1 | ENSGALP00000068491 | ENSGALP00000055141 | Rap guanine nucleotide exchange factor 3. | Heme transporter HRG1; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. Belongs to the HRG family. | 0.588 |
RAPGEF3 | TMEM106C | ENSGALP00000068491 | ENSGALP00000060315 | Rap guanine nucleotide exchange factor 3. | Transmembrane protein 106C. | 0.760 |
RPAP3 | HDAC7 | ENSGALP00000015837 | ENSGALP00000067739 | RNA polymerase II-associated protein 3; May for an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein. | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | 0.502 |