STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFI1Growth factor independent 1 transcriptional repressor. (405 aa)    
Predicted Functional Partners:
POU4F3
POU domain protein.
      
 0.843
POU4F3-2
Brain-specific homeobox/POU domain protein 3; May play a role in specifying terminally differentiated neuronal phenotypes; Belongs to the POU transcription factor family. Class-4 subfamily.
      
 0.768
PITPNM1
Uncharacterized protein.
   
 
 0.756
RUNX1
Runt-related transcription factor.
   
 
 0.719
OCM
Parvalbumin, thymic CPV3; Binds two calcium ions.
    
 
 0.718
MYO7A
Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.703
SLC26A5
Prestin.
   
  
 0.632
GATA2
GATA-binding factor 2; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes.
   
 
 0.626
LMO2
LIM domain only 2.
    
 
 0.612
TMC1
Transmembrane channel-like protein.
    
 
 0.611
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.