STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC17A8MFS domain-containing protein. (587 aa)    
Predicted Functional Partners:
SLC18A3
MFS domain-containing protein.
   
  
 0.830
OTOF
Otoferlin.
      
 0.780
TMC1
Transmembrane channel-like protein.
   
  
 0.765
SYT2
Synaptotagmin 2.
   
  
 0.736
CALB2
Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons.
   
 
 0.717
CALB1
Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
   
 
 0.715
PVALB
Parvalbumin, muscle; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity); Belongs to the parvalbumin family.
    
 
 0.710
USH1C
USH1 protein network component harmonin.
   
  
 0.706
USH1C-2
Uncharacterized protein.
      
 0.703
SDK2
Protein sidekick-2; Adhesion molecule that promotes lamina-specific synaptic connections in the retina. Expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions.
      
 0.701
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.