STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPLPeriplakin. (1777 aa)    
Predicted Functional Partners:
EVPL
SH3 domain-containing protein.
  
 
0.947
EZR
Ezrin.
   
 
 0.866
BTN3A3
Uncharacterized protein.
    
 0.754
PKP1
Plakophilin 1.
   
 
 0.678
TGM6
Transglutaminase 6.
   
 
 0.608
JUP
Plakoglobin.
   
 
 0.596
LOC101749664
TGc domain-containing protein.
      
 0.586
BFSP2
IF rod domain-containing protein; Belongs to the intermediate filament family.
      
 0.581
SCEL
LIM zinc-binding domain-containing protein.
   
  
 0.549
ZNF592
Zinc finger protein 592.
    
 
 0.536
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.