STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECTIN1Nectin cell adhesion molecule 1. (523 aa)    
Predicted Functional Partners:
AFDN
Afadin, adherens junction formation factor.
    
 0.986
NECTIN3
Nectin cell adhesion molecule 3.
    
0.979
NECTIN4
Nectin cell adhesion molecule 4.
    
0.937
PARD3
Uncharacterized protein.
    
 0.935
CADM3
Cell adhesion molecule 3.
    
 
0.912
CD226
CD226 molecule.
      
0.660
CDH17
Uncharacterized protein.
   
 
 0.629
CTNNB1
Uncharacterized protein.
    
 
 0.566
USP7
Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins, such as p53/TP53. Deubiquitinates p53/TP53, and thereby modulates p53/TP53 stability, p53/TP53-dependent transcription regulation, cell growth repression and apoptosis. May be involved in cell proliferation during early embryonic development (By similarity).
      
 0.526
LRTM2
Leucine rich repeats and transmembrane domains 2.
      
 0.496
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.