FBXL21 protein (Gallus gallus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

FBXL21

F-box domain-containing protein. (437 aa)

Predicted Functional Partners:

SKP1

0.773

CRY1

0.761

CUL1

0.709

CDCP2

0.703

PLBD1

0.676

OTUD7A

0.674

CCDC92B

0.625

CRY2

0.621

CCDC66

0.601

TCEB1

0.596

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC66	CDCP2	ENSGALP00000070638	ENSGALP00000017469	Coiled-coil domain containing 66.	CUB domain containing protein 2.	0.674
CCDC66	FBXL21	ENSGALP00000070638	ENSGALP00000058180	Coiled-coil domain containing 66.	F-box domain-containing protein.	0.601
CCDC66	OTUD7A	ENSGALP00000070638	ENSGALP00000071176	Coiled-coil domain containing 66.	OTU deubiquitinase 7A.	0.604
CCDC66	PLBD1	ENSGALP00000070638	ENSGALP00000046460	Coiled-coil domain containing 66.	Phospholipase B-like; Putative phospholipase.	0.623
CCDC92B	FBXL21	ENSGALP00000042456	ENSGALP00000058180	CCDC92 domain-containing protein.	F-box domain-containing protein.	0.625
CDCP2	CCDC66	ENSGALP00000017469	ENSGALP00000070638	CUB domain containing protein 2.	Coiled-coil domain containing 66.	0.674
CDCP2	FBXL21	ENSGALP00000017469	ENSGALP00000058180	CUB domain containing protein 2.	F-box domain-containing protein.	0.703
CDCP2	OTUD7A	ENSGALP00000017469	ENSGALP00000071176	CUB domain containing protein 2.	OTU deubiquitinase 7A.	0.706
CDCP2	PLBD1	ENSGALP00000017469	ENSGALP00000046460	CUB domain containing protein 2.	Phospholipase B-like; Putative phospholipase.	0.706
CRY1	CRY2	ENSGALP00000020598	ENSGALP00000013730	Cryptochrome-1; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	Cryptochrome-2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	0.862
CRY1	FBXL21	ENSGALP00000020598	ENSGALP00000058180	Cryptochrome-1; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	F-box domain-containing protein.	0.761
CRY1	SKP1	ENSGALP00000020598	ENSGALP00000010447	Cryptochrome-1; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.484
CRY2	CRY1	ENSGALP00000013730	ENSGALP00000020598	Cryptochrome-2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	Cryptochrome-1; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	0.862
CRY2	CUL1	ENSGALP00000013730	ENSGALP00000046909	Cryptochrome-2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	Cullin 1; Belongs to the cullin family.	0.404
CRY2	FBXL21	ENSGALP00000013730	ENSGALP00000058180	Cryptochrome-2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	F-box domain-containing protein.	0.621
CRY2	SKP1	ENSGALP00000013730	ENSGALP00000010447	Cryptochrome-2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.673
CUL1	CRY2	ENSGALP00000046909	ENSGALP00000013730	Cullin 1; Belongs to the cullin family.	Cryptochrome-2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal [...]	0.404
CUL1	FBXL21	ENSGALP00000046909	ENSGALP00000058180	Cullin 1; Belongs to the cullin family.	F-box domain-containing protein.	0.709
CUL1	SKP1	ENSGALP00000046909	ENSGALP00000010447	Cullin 1; Belongs to the cullin family.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.999
CUL1	TCEB1	ENSGALP00000046909	ENSGALP00000055188	Cullin 1; Belongs to the cullin family.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.882