STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (797 aa)    
Predicted Functional Partners:
KCND2
BTB domain-containing protein; Belongs to the potassium channel family.
   
 
 0.674
GRM1
Glutamate metabotropic receptor 1.
   
 
 0.645
PTCHD1
Patched domain containing 1.
   
  
 0.643
LONRF2
LON peptidase N-terminal domain and ring finger 2.
   
  
 0.626
CNTNAP2
Contactin associated protein like 2.
   
  
 0.610
PRNP
Major prion protein homolog; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its h [...]
    
 
 0.594
GALNT11
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.590
CADPS2
Calcium dependent secretion activator 2.
   
  
 0.589
KCND3
BTB domain-containing protein; Belongs to the potassium channel family.
   
 
 0.551
ERI3
ERI1 exoribonuclease family member 3.
      
 0.546
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.