STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERAP1Aminopeptidase. (929 aa)    
Predicted Functional Partners:
TAPBP
Tapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
   
  
 0.808
PDIA3
Protein disulfide-isomerase A3; Belongs to the protein disulfide isomerase family.
   
 
 0.724
XPNPEP3
X-prolyl aminopeptidase 3.
  
 
 0.678
XPNPEP2
X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.
  
 
 0.664
BLMH
Bleomycin hydrolase; The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity; Belongs to the peptidase C1 family.
     
 0.641
XPNPEP1
X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.
  
 
 0.621
CALR
Calreticulin.
   
  
 0.619
ACE2
Angiotensin-converting enzyme.
   
  
 0.616
CALR3
Calreticulin.
   
  
 0.609
SLC15A1
Peptide transporter PEPT1.
   
 
 0.565
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.