STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARF1Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)    
Predicted Functional Partners:
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
   
 0.957
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.915
NCKAP1
NCK associated protein 1.
   
 0.912
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.911
ARF6
ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity).
  
 
0.909
NCKAP1L
Uncharacterized protein.
   
 0.909
ABI1
Uncharacterized protein.
    
 0.906
WASF3L
WH2 domain-containing protein.
    
 0.905
WASF3
WASP family member 3.
    
 0.905
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
   
 0.875
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.