STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (507 aa)    
Predicted Functional Partners:
P2RX7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
  
  
0.666
CALHM1
Calcium homeostasis modulator 1.
      
 0.614
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.613
P2RX5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.611
P2RX4
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.610
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
      
 0.591
GPR63
G protein-coupled receptor 63.
      
 0.582
P2RY6
P2Y purinoceptor 3; Receptor for extracellular ADP > UTP > ATP = UDP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family.
      
 0.557
P2RX6
Purinergic receptor P2X 6.
  
 
 
0.532
KCNJ16
Potassium voltage-gated channel subfamily J member 16.
      
 0.519
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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