node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATXN7 | ATXN7L3 | ENSGALP00000071236 | ENSGALP00000045426 | SCA7 domain-containing protein. | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | 0.977 |
ATXN7 | ENY2 | ENSGALP00000071236 | ENSGALP00000064904 | SCA7 domain-containing protein. | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] | 0.988 |
ATXN7 | SGF29 | ENSGALP00000071236 | ENSGALP00000037055 | SCA7 domain-containing protein. | SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. | 0.905 |
ATXN7 | TADA3 | ENSGALP00000071236 | ENSGALP00000055576 | SCA7 domain-containing protein. | Transcriptional adaptor 3. | 0.897 |
ATXN7 | TAF12 | ENSGALP00000071236 | ENSGALP00000001461 | SCA7 domain-containing protein. | TFIID_20kDa domain-containing protein. | 0.923 |
ATXN7 | TRRAP | ENSGALP00000071236 | ENSGALP00000005678 | SCA7 domain-containing protein. | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.932 |
ATXN7 | USP22 | ENSGALP00000071236 | ENSGALP00000056329 | SCA7 domain-containing protein. | Ubiquitin carboxyl-terminal hydrolase. | 0.964 |
ATXN7L3 | ATXN7 | ENSGALP00000045426 | ENSGALP00000071236 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | SCA7 domain-containing protein. | 0.977 |
ATXN7L3 | ENY2 | ENSGALP00000045426 | ENSGALP00000064904 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] | 0.997 |
ATXN7L3 | PCID2 | ENSGALP00000045426 | ENSGALP00000060298 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | PCI domain-containing protein. | 0.407 |
ATXN7L3 | SGF29 | ENSGALP00000045426 | ENSGALP00000037055 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. | 0.902 |
ATXN7L3 | TADA3 | ENSGALP00000045426 | ENSGALP00000055576 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | Transcriptional adaptor 3. | 0.978 |
ATXN7L3 | TAF12 | ENSGALP00000045426 | ENSGALP00000001461 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | TFIID_20kDa domain-containing protein. | 0.962 |
ATXN7L3 | TRRAP | ENSGALP00000045426 | ENSGALP00000005678 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.977 |
ATXN7L3 | USP22 | ENSGALP00000045426 | ENSGALP00000056329 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | Ubiquitin carboxyl-terminal hydrolase. | 0.991 |
CETN3 | ENY2 | ENSGALP00000023563 | ENSGALP00000064904 | Centrin 3. | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] | 0.973 |
CETN3 | MCM3AP | ENSGALP00000023563 | ENSGALP00000066124 | Centrin 3. | MCM3AP_GANP domain-containing protein. | 0.994 |
CETN3 | PCID2 | ENSGALP00000023563 | ENSGALP00000060298 | Centrin 3. | PCI domain-containing protein. | 0.808 |
ENY2 | ATXN7 | ENSGALP00000064904 | ENSGALP00000071236 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] | SCA7 domain-containing protein. | 0.988 |
ENY2 | ATXN7L3 | ENSGALP00000064904 | ENSGALP00000045426 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. | 0.997 |