STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPON2Spondin 2. (387 aa)    
Predicted Functional Partners:
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif 17.
     
 0.640
ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif 2.
   
 
 0.629
THBS1
Uncharacterized protein.
   
 
 0.576
TOR3A
Torsin family 3 member A.
      
 0.533
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif 3.
   
 
 0.529
SPON1
Spondin-1; Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Somite-derived spondin 1 is an inhibitory signal involved in patterning the segmental migration of neural crest cells and their topographical segregation within the rostral somites in vitro. May be required to prevent the lateral drifting of the commissural axons after having crossed the floor plate.
     
0.529
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif 14.
   
 
 0.526
THBS2
Thrombospondin-2; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions; Belongs to the thrombospondin family.
   
 
 0.520
THSD4
Thrombospondin type 1 domain containing 4.
     
 0.518
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif 15.
   
 
 0.514
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.