STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RLFRearranged L-myc fusion. (1901 aa)    
Predicted Functional Partners:
C1H21ORF91
Protein EURL; Plays a role in cortical progenitor cell proliferation and differentiation. May promote dendritic spine development of post- migratory cortical projection neurons by modulating the beta-catenin signaling pathway; Belongs to the EURL family.
   
  
 0.787
FAM183A
Uncharacterized protein.
      
 0.783
UAP1
UDP-N-acetylglucosamine pyrophosphorylase 1.
      
 0.761
FBXL17
F-box and leucine rich repeat protein 17.
   
 
 0.758
KLHL7
Kelch-like protein 7; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination (By similarity).
   
 
 0.757
UFC1
Uncharacterized protein.
      
 0.732
TBCB
CAP-Gly domain-containing protein.
    
 
 0.710
TMEM39A
Transmembrane protein 39A.
      
 0.707
SMCHD1
Structural maintenance of chromosomes flexible hinge domain containing 1.
   
  
 0.657
CSNK2B
Casein kinase II subunit beta; Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity).
    
 
 0.593
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.