STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRCAMNeuronal cell adhesion molecule; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Specifically involved in the development of optic fibres in the retina; Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. (1836 aa)    
Predicted Functional Partners:
CNTN2
Contactin-2; Axon-associated cell adhesion molecule (AxCAM) which promotes neurite outgrowth by interaction with the AxCAM L1 (G4) of neuritic membrane. Contributes to the organization of axonal domains at nodes of Ranvier (By similarity).
   
0.975
CNTN1
Contactin-1; Mediates cell surface interactions during nervous system development. Interaction with TNR enhances the neurite outgrowth. Belongs to the immunoglobulin superfamily. Contactin family.
   
0.958
GLDN
Gliomedin.
      
 0.944
SEMA3B
Semaphorin 3B.
    
 
 0.803
SEMA6D
Semaphorin 6D; Belongs to the semaphorin family.
    
 
 0.748
ANK3
Uncharacterized protein.
    
 
 0.738
PLXNA1
Plexin A1.
    
 
 0.738
ANK1
Ankyrin 1.
    
 
 0.726
CNTN5
Contactin-5; Contactins mediate cell surface interactions during nervous system development. May contribute to the formation of somatotopic maps of cerebellar afferents during the development of the nervous system. Belongs to the immunoglobulin superfamily. Contactin family.
   
 
0.724
PTPRG
Receptor-type tyrosine-protein phosphatase gamma; Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
    
 
 0.686
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.