node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRK | KIDINS220 | ENSGALP00000004174 | ENSGALP00000067787 | Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity). | Kinase D interacting substrate 220. | 0.924 |
CRK | NTRK1 | ENSGALP00000004174 | ENSGALP00000021606 | Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity). | High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] | 0.615 |
CRK | RAP1A | ENSGALP00000004174 | ENSGALP00000002236 | Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity). | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.659 |
HIVEP1 | KIDINS220 | ENSGALP00000020761 | ENSGALP00000067787 | Human immunodeficiency virus type I enhancer binding protein 1. | Kinase D interacting substrate 220. | 0.553 |
HIVEP1 | TBC1D24 | ENSGALP00000020761 | ENSGALP00000047723 | Human immunodeficiency virus type I enhancer binding protein 1. | Uncharacterized protein. | 0.539 |
HIVEP1 | TUBGCP6 | ENSGALP00000020761 | ENSGALP00000053654 | Human immunodeficiency virus type I enhancer binding protein 1. | Tubulin gamma complex associated protein 6. | 0.616 |
KIDINS220 | CRK | ENSGALP00000067787 | ENSGALP00000004174 | Kinase D interacting substrate 220. | Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity). | 0.924 |
KIDINS220 | HIVEP1 | ENSGALP00000067787 | ENSGALP00000020761 | Kinase D interacting substrate 220. | Human immunodeficiency virus type I enhancer binding protein 1. | 0.553 |
KIDINS220 | MAGI2 | ENSGALP00000067787 | ENSGALP00000072773 | Kinase D interacting substrate 220. | Uncharacterized protein. | 0.738 |
KIDINS220 | NTRK1 | ENSGALP00000067787 | ENSGALP00000021606 | Kinase D interacting substrate 220. | High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] | 0.613 |
KIDINS220 | OLFM1 | ENSGALP00000067787 | ENSGALP00000003955 | Kinase D interacting substrate 220. | Noelin; Contributes to the regulation of axonal growth (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube. | 0.707 |
KIDINS220 | RAP1A | ENSGALP00000067787 | ENSGALP00000002236 | Kinase D interacting substrate 220. | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.550 |
KIDINS220 | RND1 | ENSGALP00000067787 | ENSGALP00000049202 | Kinase D interacting substrate 220. | Rho family GTPase 1. | 0.621 |
KIDINS220 | TBC1D24 | ENSGALP00000067787 | ENSGALP00000047723 | Kinase D interacting substrate 220. | Uncharacterized protein. | 0.608 |
KIDINS220 | TENM4 | ENSGALP00000067787 | ENSGALP00000052932 | Kinase D interacting substrate 220. | Uncharacterized protein. | 0.637 |
KIDINS220 | TUBGCP6 | ENSGALP00000067787 | ENSGALP00000053654 | Kinase D interacting substrate 220. | Tubulin gamma complex associated protein 6. | 0.727 |
MAGI2 | KIDINS220 | ENSGALP00000072773 | ENSGALP00000067787 | Uncharacterized protein. | Kinase D interacting substrate 220. | 0.738 |
NTRK1 | CRK | ENSGALP00000021606 | ENSGALP00000004174 | High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] | Adapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity). | 0.615 |
NTRK1 | KIDINS220 | ENSGALP00000021606 | ENSGALP00000067787 | High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] | Kinase D interacting substrate 220. | 0.613 |
NTRK1 | RAP1A | ENSGALP00000021606 | ENSGALP00000002236 | High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.540 |