STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK2Trypsin inhibitor ClTI-1; Inhibits trypsin and plasmin. (114 aa)    
Predicted Functional Partners:
SPACA1
Sperm acrosome associated 1.
      
 0.844
ACRL
Acrosin-b; Belongs to the peptidase S1 family.
    
 
 0.722
BRINP2
BMP/retinoic acid inducible neural specific 2.
      
 0.701
ACR
Acrosin-a; Belongs to the peptidase S1 family.
    
 
 0.611
HEXA
Beta-hexosaminidase.
      
 0.601
SYCE3
Uncharacterized protein.
      
 0.601
SPINK5
Ovoinhibitor; Seems to have at least five active inhibitory domains; two for trypsin, two for chymotrypsin and one for elastase.
      
0.554
LOC101749216
Kazal-like domain-containing protein.
  
   
0.535
SPAG6
Uncharacterized protein.
      
 0.533
SPIA5
SERPIN domain-containing protein; Belongs to the serpin family.
      
 0.521
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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