STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100857280PKS_ER domain-containing protein. (404 aa)    
Predicted Functional Partners:
ESD
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 0.951
ADHFE1
Fe-ADH domain-containing protein.
  
 0.858
ADH1C
Alcohol dehydrogenase 1.
  
  
0.806
PLAC8
Uncharacterized protein.
      
 0.704
PLAC8L1
Uncharacterized protein.
      
 0.704
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
  
 0.638
CENPV
GFA domain-containing protein.
    
 0.617
MKL2
SAP domain-containing protein.
   
 0.574
MMACHC
Methylmalonic aciduria and homocystinuria type C protein homolog; Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate. Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione- dependent reductive demethylation of adenosylcobalamin. Under anaerobic conditions cob(I)alamin is the first product; it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen. Binds cyanocobalamin, adenosylcobalamin, methylcobalami [...]
   
 
 0.541
MYO1E
Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.534
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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